GI & Digestive

What Causes Pain in the Lower Right Abdomen?

Andre Stone | MD

Medically reviewed by Andre Stone | MD, University of Pittsburgh School of Medicine on August 25th, 2026.

Lower right abdominal pain can stem from several conditions, including appendicitis and other problems that may require urgent treatment. The appendix, a small tube attached to the large intestine, becomes inflamed in approximately 1 in 1,000 people annually. Other common causes include ovarian cysts in women, kidney stones, urinary tract infections, and muscle strain. Digestive issues like inflammatory bowel disease or food poisoning can also trigger pain in this area. Additionally, hernias occur when tissue pushes through weakened abdominal muscles, affecting about 5% of the population. The pain's intensity, duration, and accompanying symptoms can help a clinician identify the cause. Seek urgent medical care for severe or worsening pain, fainting or dizziness, persistent vomiting, fever, blood in the stool or urine, a swollen or very tender abdomen, or pain with possible pregnancy.

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