March 31, 2026 Symptoms & General Health

What Causes Numbness and Tingling in Your Hands?

Medically reviewed by Andre Stone | MD, University of Pittsburgh School of Medicine on August 25th, 2026.

Numbness and tingling in hands typically result from nerve compression, circulation problems, or underlying medical conditions. The most common cause is carpal tunnel syndrome, affecting over 3 million Americans annually when the median nerve becomes compressed at the wrist. Other frequent causes include cervical radiculopathy from neck problems, diabetes affecting peripheral nerves, and vitamin B12 deficiency. Temporary causes include sleeping in awkward positions, repetitive motions, or cold temperatures. More serious conditions like multiple sclerosis, stroke, or autoimmune disorders can also trigger these symptoms. Seek medical evaluation if numbness persists, keeps returning, or has no clear temporary cause. Call emergency services immediately if numbness begins suddenly—especially on one side—or occurs with weakness, facial drooping, trouble speaking, confusion, severe dizziness, or a sudden severe headache.