What Causes Burning Sensation in the Stomach?
Medically reviewed by Andre Stone | MD, University of Pittsburgh School of Medicine on August 25th, 2026.
A burning sensation in the upper abdomen can have several causes. GERD is one possibility, especially when burning rises into the chest or throat, because stomach contents flow backward into the esophagus. Peptic ulcers, often caused by H. pylori bacteria or NSAIDs, create painful sores that burn when exposed to acid. Gastritis, or inflammation of the stomach lining, can be associated with H. pylori infection, heavy alcohol use, certain medications, autoimmune disease, or severe physical stress from major illness or injury. Spicy foods, caffeine, and large meals may trigger or worsen symptoms in some people, although triggers vary and do not always work by increasing acid production. Other causes include hiatal hernias and certain autoimmune conditions.
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