Ciprofloxacin can cause both common and serious side effects. The most frequent side effects include nausea, diarrhea, dizziness, and headache, affecting 1-10% of patients. More concerning reactions include tendon problems (especially Achilles tendon rupture), nerve damage, and central nervous system effects like confusion or seizures. Serious side effects occur in approximately 1-3% of users. The FDA has issued black box warnings for increased risks of tendonitis, tendon rupture, and worsening of myasthenia gravis. Other notable side effects include QT interval prolongation, photosensitivity, and C. difficile-associated diarrhea. If you experience severe joint pain, numbness, or mental changes while taking ciprofloxacin, contact your healthcare provider immediately.
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