Pregnancy & Medication Safety

Is It Safe to Take Aspirin During Pregnancy?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 21st, 2026.

Low-dose aspirin (81mg) is generally safe during pregnancy when prescribed by a healthcare provider. The American College of Obstetricians and Gynecologists recommends low-dose aspirin for women at high risk of preeclampsia, typically starting between 12-28 weeks of pregnancy. However, regular-strength aspirin (325mg or higher) should be avoided, especially in the third trimester, as it can increase bleeding risks during delivery and may cause complications for the baby. Studies show that low-dose aspirin reduces preeclampsia risk by up to 24% in high-risk pregnancies. Always consult your doctor before taking any aspirin during pregnancy, as individual risk factors vary significantly.

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