How Long After Taking Levothyroxine Can You Eat?

You should wait at least 30 to 60 minutes after taking levothyroxine before eating. The FDA recommends taking levothyroxine on an empty stomach, ideally 30-60 minutes before breakfast, to ensure optimal absorption. Food can reduce levothyroxine absorption by up to 40%, particularly foods high in fiber, calcium, or iron. Coffee, even black coffee, can also interfere with absorption and should be avoided for at least 30 minutes. For best results, take your medication at the same time each morning with a full glass of water, then wait before consuming any food or beverages other than water.