Does Testosterone Replacement Therapy Affect Fertility?

Yes, testosterone replacement therapy typically reduces male fertility by suppressing natural sperm production. TRT shuts down the body's natural testosterone production through negative feedback on the hypothalamic-pituitary-gonadal axis, which can decrease sperm count by up to 90% within months. Studies show that 65-70% of men on TRT experience significant drops in sperm concentration and motility. The effect is usually reversible, with fertility potentially recovering 3-6 months after discontinuing treatment, though some men may require additional interventions like HCG or clomiphene citrate to restore normal sperm production.

Related Questions

• How long does it take for fertility to return after stopping TRT?

• Can you take testosterone and still maintain fertility?

• What are alternatives to TRT that preserve fertility?

• Does HCG help maintain fertility during testosterone therapy?

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