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Understanding TRT Side Effects
March 31st, 2026

Does Testosterone Replacement Cause Hair Loss?

Testosterone replacement therapy can accelerate hair loss in men genetically predisposed to male pattern baldness. TRT increases dihydrotestosterone (DHT) levels, which shrinks hair follicles and causes androgenic alopecia. Studies show that 50-80% of men experience some degree of hair thinning by age 50, with testosterone and DHT being primary drivers. However, TRT doesn't cause hair loss in men without genetic susceptibility. The rate and severity depend on individual genetics, dosage, and treatment duration. Men already experiencing hair loss may notice acceleration within 3-6 months of starting therapy. Those with strong family histories of baldness should discuss hair loss prevention strategies with their healthcare provider before beginning TRT.

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