Does Spironolactone Help with Hormonal Acne?

Spironolactone can help treat acne influenced by androgens by blocking androgen effects and reducing oil production. This prescription medication works particularly well for adult women with persistent acne along the jawline, chin, and lower face. Common doses include 50–100 mg daily, although the appropriate dose varies. Improvement often takes several months, and results differ from person to person. Spironolactone is especially beneficial for women whose acne worsens with menstrual cycles or those who haven't responded well to topical treatments. Spironolactone can raise potassium and lower blood pressure. A clinician may check blood pressure, kidney function, or potassium based on a person’s age, health conditions, dose, and other medications. A dermatologist may combine spironolactone with a topical treatment, such as a retinoid, depending on the patient’s needs and tolerance.