Does PCOS Make It Harder to Get Pregnant?
Medically reviewed by Andre Stone | MD, University of Pittsburgh School of Medicine on August 25th, 2026.
PCOS can make it harder to get pregnant, mainly when it causes irregular or absent ovulation. The degree of difficulty varies, and many women with PCOS conceive naturally or with treatment. The main issue is often irregular or absent ovulation related to the hormonal and metabolic changes associated with PCOS, which may include higher androgen or insulin levels. Women with PCOS may ovulate only a few times per year instead of monthly, dramatically reducing conception chances. Insulin resistance is common in PCOS and may contribute to ovulation and fertility problems, although it does not affect everyone with the condition. However, many women with PCOS conceive successfully, either naturally or with treatment. Options may include lifestyle support when appropriate, ovulation-inducing medication—often letrozole as the first choice—and, in some cases, metformin or assisted reproductive technologies. Treatment should be tailored with a clinician.
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