Does Nexplanon Cause Weight Gain?
Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 21st, 2026.
Nexplanon can cause weight gain in some users, though significant weight gain is relatively uncommon. Clinical studies show that about 13.7% of women using Nexplanon experienced weight gain of 7% or more from their baseline weight over two years. The average weight gain reported in studies ranges from 3-5 pounds during the first year of use. Weight changes vary significantly between individuals, with some users experiencing weight loss instead. The progestin hormone in Nexplanon (etonogestrel) can affect metabolism, appetite, and fluid retention, contributing to weight fluctuations. If you're concerned about weight changes after Nexplanon insertion, track your weight regularly and discuss any significant changes with your healthcare provider.
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