Does Metformin Affect Sexual Performance in Men?
Medically reviewed by Andre Stone | MD, University of Pittsburgh School of Medicine on August 25th, 2026.
Metformin is not generally recognized as a common direct cause of sexual dysfunction, but research on its effects in men is limited and mixed. Some studies suggest it may help erectile function in certain men with insulin resistance, while others have raised concerns about lower testosterone, reduced sex drive, or erectile difficulties. A small clinical study found improved erectile-function scores when metformin was added for insulin-resistant men who had responded poorly to sildenafil, but the participants did not have diabetes and the findings require confirmation in larger studies. The drug's ability to enhance blood sugar control and vascular health can support better circulation, which is crucial for sexual performance. However, some men may experience gastrointestinal side effects that could indirectly affect libido or comfort during intimacy. If you're experiencing sexual dysfunction while taking metformin, consult your healthcare provider to evaluate other potential causes and treatment options.
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