Does Gabapentin Cause Weight Gain?

Yes, gabapentin can cause weight gain, though it affects only about 1-6% of users. Clinical studies show the average weight gain ranges from 5-15 pounds over several months of treatment. The weight gain appears to result from increased appetite and changes in metabolism rather than fluid retention. Factors that increase risk include higher doses, longer treatment duration, and pre-existing metabolic conditions. The weight gain is typically gradual and may stabilize after the first few months. If you experience significant weight changes while taking gabapentin, discuss dosage adjustments or alternative medications with your healthcare provider.

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