Does Gabapentin Affect Sexual Performance in Men?

Yes, gabapentin can affect sexual performance in men, though it's less common than with some other medications. Studies indicate that 3-5% of men taking gabapentin experience sexual side effects, including decreased libido, difficulty achieving or maintaining erections, and delayed orgasm. The mechanism involves gabapentin's effects on neurotransmitters that regulate sexual function, particularly in the central nervous system. Higher doses (above 1800mg daily) appear to increase the likelihood of sexual side effects. Most sexual dysfunction symptoms are reversible and typically improve within weeks of dose reduction or discontinuation. If you're experiencing sexual side effects from gabapentin, discuss alternatives with your doctor rather than stopping the medication abruptly.