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Does Doxycycline Make You Sensitive to the Sun?

Andre Stone | MD

Medically reviewed by Andre Stone | MD, University of Pittsburgh School of Medicine on August 25th, 2026.

Yes, doxycycline significantly increases your sensitivity to sunlight, a side effect called photosensitivity. This antibiotic can make your skin more likely to burn, sometimes after less sun exposure than usual. The reaction can resemble an exaggerated sunburn and may sometimes include redness, pain, swelling, or blistering after sun exposure. Skin-color changes can occasionally persist after the reaction heals. Photosensitivity affects some people taking doxycycline, but reported rates vary depending on the dose, condition being treated, and amount of sun exposure. To prevent sun damage, use broad-spectrum SPF 30+ sunscreen, wear protective clothing, and avoid direct sunlight between 10 AM and 4 PM while taking this medication.

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