Does Atorvastatin Cause Muscle Pain?
Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 21st, 2026.
Yes, atorvastatin can cause muscle pain in approximately 10-15% of patients. This side effect, known as statin-associated muscle symptoms (SAMS), typically presents as muscle aches, weakness, or cramping, particularly in the legs, shoulders, or back. The pain usually develops within weeks to months of starting treatment and ranges from mild discomfort to severe myopathy. Risk factors include higher doses, older age, kidney disease, and certain drug interactions. Most cases resolve within weeks after discontinuing the medication, though some patients experience lingering symptoms. If you develop unexplained muscle pain while taking atorvastatin, contact your healthcare provider promptly to discuss dose adjustment or alternative treatments.
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