Medication Guides

Does Apple Cider Vinegar Interact with Any Medications?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 20th, 2026.

Yes, apple cider vinegar can interact with several medications, potentially causing dangerous side effects. It may enhance the effects of diabetes medications like insulin and metformin, leading to dangerously low blood sugar levels. Apple cider vinegar can also increase potassium loss when combined with diuretics or digoxin, potentially causing heart rhythm problems. Studies show it delays stomach emptying by up to 10%, which can affect how quickly medications are absorbed. Always consult your healthcare provider before adding apple cider vinegar to your routine if you take any prescription medications.

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