Can You Take Tadalafil with Metoprolol?
Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 20th, 2026.
Yes, tadalafil and metoprolol can generally be taken together, but this combination requires medical supervision due to potential blood pressure effects. Both medications can lower blood pressure, and when combined, they may cause excessive hypotension in some patients. Studies show that concurrent use can result in blood pressure drops of 10-15 mmHg systolic. Your doctor will likely start with lower doses and monitor your response carefully. Common side effects of this combination include dizziness, lightheadedness, and fatigue. If you experience chest pain, severe dizziness, or fainting, seek immediate medical attention. Always inform your healthcare provider about all medications you're taking before starting either drug.
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