Symptoms & General Health

Can Low Magnesium Contribute to Anxiety?

Faith Coleman

Medically reviewed by Faith Coleman, University of New Mexico School of Medicine on August 20th, 2026.

Yes, low magnesium levels can contribute to anxiety symptoms. About 50 percent of American adults do not get the recommended daily intake of magnesium. Magnesium effects neurotransmitter function, including GABA, which helps regulate mood and stress responses. Studies show that magnesium supplementation can reduce anxiety symptoms, especially in deficient individuals. Common signs of magnesium deficiency include muscle cramps, fatigue, loss of appetite, nausea, weakness, and heightened stress sensitivity. The recommended daily intake is 400-420mg for men and 310-320mg for women. Blood tests can accurately measure serum magnesium levels, though normal serum levels don't always reflect tissue stores.

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