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Can Gabapentin Help with Anxiety?
Off-Label Anxiety Treatment Options
March 31st, 2026
Can Gabapentin Help with Anxiety?
Gabapentin can help with certain anxiety disorders, though it's not FDA-approved for this use. Studies show gabapentin may reduce anxiety symptoms in 40-60% of patients with social anxiety disorder and generalized anxiety disorder. The medication works by affecting calcium channels in the brain, which can have a calming effect. Typical anxiety doses range from 300-900mg daily, often starting lower and gradually increasing. However, gabapentin carries risks including dizziness, sedation, and potential dependence with long-term use. It's most commonly prescribed off-label when first-line anxiety treatments haven't worked effectively. Always consult your healthcare provider before using gabapentin for anxiety, as they can evaluate whether it's appropriate for your specific situation and medical history.
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