GI & Digestive

Can Celiac Disease Develop in Adults?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 20th, 2026.

Yes, celiac disease can develop at any age, including adulthood. While many people are diagnosed as children, studies show that over 60% of celiac diagnoses occur in adults over age 20. The condition involves an autoimmune response to gluten that damages the small intestine's lining. Adult-onset celiac disease often presents with different symptoms than childhood cases, including fatigue, bone pain, depression, and iron deficiency anemia rather than classic digestive symptoms. Genetic predisposition combined with environmental triggers like stress, pregnancy, surgery, or infections can activate the disease later in life. If you suspect celiac disease, consult a healthcare provider for proper testing before starting a gluten-free diet.

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