Understanding Sentinel Lymph Node Biopsy in Melanoma
Published: Jun 15, 2024
Sentinel lymph node biopsy is a key test in melanoma staging. It helps determine whether cancer has spread to the lymph nodes.
Contents
What Is a Sentinel Lymph Node Biopsy?
A sentinel lymph node biopsy is a procedure used to find out if melanoma has spread beyond the primary tumor. The 'sentinel' node is the first lymph node that cancer cells are likely to spread to from the primary tumor. A biopsy of this node helps doctors decide on the most effective treatment plan.
Why Is It Important?
This test aids in accurate staging, which is crucial for determining the prognosis and treatment strategy. Patients with melanoma that has spread to the sentinel lymph node may require more aggressive treatment compared to those whose lymph nodes are clear.

How Is It Done?
During the procedure, a special dye or radioactive substance is injected near the tumor. This substance travels to the sentinel lymph node, which is then surgically removed and examined for cancer cells. If cancer is found, further lymph nodes may need to be removed.
Frequently Asked Questions
It's the first lymph node likely to be affected by spreading cancer cells.
It helps determine if cancer has spread and informs treatment decisions.
A dye is injected to locate the node, which is then removed and tested.
You may need more lymph nodes removed and additional treatment.
The Bottom Line
A sentinel lymph node biopsy provides critical information for melanoma treatment.
References
- El Sharouni MA, Stodell MD, Ahmed T, et al. Sentinel node biopsy in patients with melanoma improves the accuracy of staging when added to clinicopathological features of the primary tumor. Ann Oncol 2021; 32:375.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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