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Wellbutrin (bupropion HCl ER XL) is FDA-approved for the treatment of major depressive disorder and seasonal affective disorder. It is also prescribed off-label as an aid for smoking cessation under the brand name Zyban, which contains the same active ingredient.

Wellbutrin is an NDRI (norepinephrine-dopamine reuptake inhibitor), not an SSRI. Unlike SSRIs, it does not typically cause sexual dysfunction or weight gain, which makes it a preferred alternative for patients who experience those side effects with other antidepressants.

Most patients begin to notice improvement in mood and energy within 2 to 4 weeks of starting Wellbutrin, though the full therapeutic effect may take 6 to 8 weeks. Consistent daily use at the prescribed dose is important for best results.

Wellbutrin is contraindicated in people with a current or past seizure disorder, a current or prior diagnosis of anorexia nervosa or bulimia nervosa, and those who have recently stopped using alcohol or benzodiazepines abruptly, as it can lower the seizure threshold. Your physician will review your history to confirm it is safe for you.

Wellbutrin can interact with a number of medications, including MAO inhibitors, certain antipsychotics, and other antidepressants. Always provide your physician with a complete list of all prescription and over-the-counter medications and supplements you are taking.

Common side effects include dry mouth, headache, nausea, insomnia, and increased sweating. These effects are often mild and tend to improve after the first few weeks. Contact your physician promptly if you experience unusual mood changes, agitation, or any new or worsening symptoms.

Doctronic uses an AI-guided evaluation to gather your health history and current symptoms. A licensed physician then reviews your information, confirms whether a refill is appropriate, and issues a treatment plan or prescription. The entire process is doctor-reviewed and audited to ensure your safety.

Yes. Doctronic's care is provided by licensed physicians who are board-eligible or board-certified in their respective states. All consultations are HIPAA-aligned, and your personal health information is protected using industry-standard security practices. Doctronic is available to adults 18 and older in any U.S. state.