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Glyxambi combines two proven diabetes medications into one convenient daily pill. Connect with a licensed physician on Doctronic to find out if Glyxambi is right for your type 2 diabetes management.

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Medications We Prescribe for Type 2 Diabetes

Glyxambi

Empagliflozin-Linagliptin

The featured combination SGLT2 inhibitor and DPP-4 inhibitor for type 2 diabetes management.

Get Glyxambi online Drug Info

Qtern

Dapagliflozin-Saxagliptin

Another SGLT2 inhibitor and DPP-4 inhibitor combination option for type 2 diabetes blood sugar control.

Get Qtern online Drug Info

Jardiance

Empagliflozin

An SGLT2 inhibitor that lowers blood sugar by increasing glucose excretion through the kidneys.

Get Jardiance online Drug Info

Fortamet

Metformin

A foundational oral diabetes medication that reduces hepatic glucose production and improves insulin sensitivity.

Get Fortamet online Drug Info

Pricing that won't make you sick

Chat for free, see an online doctor for $39/visit, or renew a prescription online for as low as $0

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These are stories from real users who turned to Doctronic for answers when it mattered most.

  • Preparing for a doctor visit
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How Type 2 Diabetes Treatment Works at Doctronic


Start a Free Chat With Doctronic

Doctronic answers your health questions with personalized medical insights and helps our doctors create a better treatment plan for you.


Meet With a Licensed Doctor For Treatment

Book a $39 telehealth appointment (or copay), with an average wait of about 5 minutes. Our doctors create personalized treatment plans with prescriptions when needed.


Pick Up Your Prescription

Our doctors prescribe non-controlled medications in all 50 states and send prescriptions to your pharmacy for same-day pickup.

Hear from our users

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JustAnswer Customer June 23, 2026

What Is Glyxambi?

Glyxambi (empagliflozin-linagliptin) is a prescription medication used to manage type 2 diabetes in adults. It works by combining two complementary mechanisms: empagliflozin, an SGLT2 inhibitor, removes excess glucose through the urine, while linagliptin, a DPP-4 inhibitor, helps the pancreas release more insulin after meals and reduces excess glucagon. With the right dose and ongoing monitoring, Glyxambi can help lower blood sugar levels as part of a comprehensive diabetes care plan that includes diet and exercise.

  • Two-in-one pill combining an SGLT2 inhibitor and a DPP-4 inhibitor for blood sugar control
  • Get personalized guidance from doctor-trained AI
  • Explore treatment and prescription options

Is Online Glyxambi Treatment Right for You?

Glyxambi is indicated for adults with type 2 diabetes whose blood sugar is not adequately controlled on a single oral diabetes medication or who would benefit from combination therapy in one tablet. It is not intended for type 1 diabetes or diabetic ketoacidosis and requires a valid prescription from a licensed physician.

Because Glyxambi affects kidney function and cardiovascular health, your physician will review your kidney function, history of urinary tract infections, heart conditions, and other metabolic factors before prescribing. Sharing a complete medical history helps ensure this medication is safe and appropriate for you.

  • Diagnosed with type 2 diabetes
  • Get personalized guidance from AI and clinicians
  • Explore treatment and prescription refill options
  • Access care from home, often the same day
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Diagnosed with type 2 diabetes Fasting blood sugar above 126 mg/dL or HbA1c above 6.5% Experiencing high blood sugar symptoms (increased thirst, frequent urination, fatigue) Need a prescription refill Adults 18+ in any U.S. state

Frequently asked questions

Glyxambi is a prescription combination tablet containing empagliflozin and linagliptin. Empagliflozin is an SGLT2 inhibitor that causes the kidneys to remove excess glucose through urine. Linagliptin is a DPP-4 inhibitor that increases insulin release in response to meals and lowers excess glucagon levels. Together they address blood sugar from two different angles in a single daily dose.

Glyxambi is approved for adults with type 2 diabetes who need additional blood sugar control beyond what a single oral medication provides. It is not approved for type 1 diabetes and should not be used in people with severe kidney impairment or a history of serious hypersensitivity to either component. A licensed physician will review your full health history before prescribing.

Common side effects include urinary tract infections, genital yeast infections, and increased urination, which are associated with the SGLT2 inhibitor component. Upper respiratory tract infections and nasopharyngitis are also frequently reported. Rare but serious risks include diabetic ketoacidosis, Fournier's gangrene, and a significant drop in blood pressure, particularly in people who are dehydrated or on diuretics.

Glyxambi is taken orally once daily in the morning, with or without food. The tablet comes in two strengths (10 mg/5 mg and 25 mg/5 mg). Your physician will determine the appropriate starting dose based on your current medications, kidney function, and blood sugar control goals. Do not split or crush the tablet.

Yes. Glyxambi is commonly used as an add-on to other diabetes medications such as metformin or insulin. However, combining it with insulin or insulin secretagogues may increase the risk of low blood sugar. Your physician will review all your current medications to ensure the combination is safe and effective.

Yes. Your physician will typically check kidney function (eGFR and serum creatinine) before starting Glyxambi and periodically thereafter, since the empagliflozin component works through the kidneys and is less effective at lower kidney function levels. Regular HbA1c testing is also recommended to track blood sugar control over time.

Doctronic uses an AI-powered evaluation to gather your symptoms, medical history, and current medications. A licensed physician then reviews your information and, if appropriate, creates a personalized treatment plan that may include a Glyxambi prescription. The entire process is HIPAA-aligned and conducted by board-certified physicians.

Yes. Doctronic is a telehealth platform staffed by licensed physicians whose prescribing decisions are doctor-reviewed and regularly audited for quality and safety. All patient data is protected under HIPAA. Doctronic serves adults 18 and older in any U.S. state.