Unmasking the Causes of Cutaneous Squamous Cell Carcinoma
Published: Jun 11, 2024
Cutaneous squamous cell carcinoma (cSCC) is linked to several risk factors. Understanding these can help you minimize your risk.
Contents
The Role of UV Radiation
The primary cause of cSCC is excessive exposure to ultraviolet (UV) radiation from the sun or tanning beds. This exposure causes DNA damage in skin cells, leading to cancer over time. Protecting your skin from UV rays is essential to prevent this damage.
Additional Risk Factors
Beyond UV exposure, other risk factors include having fair skin, a family history of skin cancer, and certain genetic conditions. Aging and immunosuppression also increase the risk of developing cSCC. Understanding these factors can guide preventive measures.

Environmental Exposures
Certain environmental exposures, such as arsenic and ionizing radiation, have been linked to cSCC. People working in environments with these substances should take extra precautions to protect their skin.
Frequently Asked Questions
Excessive UV radiation exposure is the leading cause.
Fair skin, family history, and genetic conditions are notable factors.
Yes, exposures like arsenic and radiation are linked to increased risk.
Wrapping Up
Understanding the causes of cSCC empowers you to take preventive actionβwhat's your next move?
References
- Que SKT, Zwald FO, Schmults CD. Cutaneous squamous cell carcinoma: Incidence, risk factors, diagnosis, and staging. J Am Acad Dermatol 2018; 78:237.
- Kraemer KH, DiGiovanna JJ, Moshell AN, et al. Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin. N Engl J Med 1988; 318:1633.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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