Memantine: A New Hope for Advanced Alzheimer's?

Understanding Memantine

Memantine works as an NMDA receptor antagonist, helping to regulate glutamate activity in the brain. This is important because excessive glutamate can lead to brain cell damage. Memantine is thought to protect brain cells and improve symptoms in moderate to severe Alzheimer's cases.

Combining Treatments

Memantine is often used in combination with cholinesterase inhibitors for improved results. Studies show that this combination can lead to modest improvements in cognition and daily activities, especially in those with advanced Alzheimer's. However, it's important to consider patient-specific factors like drug tolerability and cost.

Memantine's Side Effects

Memantine is generally well-tolerated, with dizziness being the most common side effect. Unlike some other treatments, it doesn't significantly increase the risk of confusion or hallucinations. This makes it a viable option for many patients with advanced Alzheimer's.

Frequently Asked Questions

Key Takeaways

Memantine offers hope for those with advanced Alzheimer's, but personalized treatment is key.

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