Exploring Therapy Options for von Willebrand Disease: What's the Best Fit for You?
Published: Oct 21, 2023
Choosing the right therapy for von Willebrand disease can make a big difference in managing symptoms and improving quality of life.
Contents
DDAVP and VWF Concentrates
DDAVP is typically effective for minor bleeding, especially in Type 1 VWD patients. For those who do not respond to DDAVP, VWF concentrates are the next option. VWF concentrates can stabilize factor VIII and are useful in more severe cases or prolonged bleeding.
Antifibrinolytic Agents
Antifibrinolytic agents like tranexamic acid help stabilize blood clots and are particularly effective for mucosal bleeds. These agents can be used alone or in conjunction with other therapies, depending on the severity and location of the bleeding.
Topical Treatments and Estrogens
Topical agents like thrombin can be applied directly to bleeding areas, providing quick relief. Estrogens, often in the form of oral contraceptives, can be used to manage heavy menstrual bleeding in women with VWD.
Frequently Asked Questions
DDAVP increases VWF levels to manage minor bleeding.
They are used when DDAVP is ineffective or for severe cases.
They stabilize clots and are effective for mucosal bleeds.
Key Takeaways
Choosing the right therapy is crucial for effective management of von Willebrand disease.
Explore therapy options: Speak with Doctronic to find the best treatment for you.Related Articles
References
Federici AB, Mazurier C, Berntorp E, et al. Biologic response to desmopressin in patients with severe type 1 and type 2 von Willebrand disease: results of a multicenter European study. Blood 2004; 103:2032.
Always discuss health information with your healthcare provider.