Does Wegovy Cause Hair Loss? Understanding the Potential Side Effect

Alan Lucks | MD

Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on February 5th, 2026.

Key Takeaways

  • Semaglutide (Wegovy) may increase hair loss risk by 52%

  • Rapid weight loss and nutrient changes could contribute to hair loss

  • Women appear to be more susceptible to this side effect

  • Consultation with a healthcare provider is recommended before starting treatment

Weight loss medications like Wegovy have transformed how many approach obesity and weight management. However, recent research has raised important questions about potential side effects, particularly hair loss. Understanding the connection between prescription medications for weight loss and hair health is crucial for patients considering this treatment.

Wegovy, a brand of semaglutide, has gained significant popularity for its effectiveness in weight loss. While the medication offers promising results for weight management, emerging studies suggest potential hair loss as a notable side effect. Researchers are working to understand the mechanisms behind this phenomenon and its implications for patients.

The Research Behind Hair Loss and Wegovy

A comprehensive study from the University of British Columbia examined the relationship between semaglutide and hair loss. Researchers compared oral weight loss medication options and found some compelling evidence about potential hair loss risks.

The study analyzed data from 16 million patients, focusing on 1,926 semaglutide users. Results showed a 52% higher risk of hair loss compared to users of alternative weight loss medications. Interestingly, women seemed particularly vulnerable, with more than two times the risk of experiencing hair loss.

Potential Mechanisms of Hair Loss

Several factors might contribute to hair loss while using Wegovy:

  1. Physiological Stress from Rapid Weight Loss Sudden, significant weight reduction can disrupt the natural hair growth cycle. The impacts of weight loss on overall health can trigger temporary hair shedding.

  2. Nutritional Deficiencies Semaglutide suppresses appetite, which might lead to reduced nutrient intake. Protein deficiencies, in particular, can directly impact hair health and growth.

  3. Hormonal Changes The medication may induce hormonal shifts that potentially increase the likelihood of androgenic alopecia, a common form of hair loss.

Who is Most at Risk?

While the study suggests women might be more susceptible, more research is needed to confirm gender-specific risks. Patients with pre-existing nutritional challenges or hormonal imbalances may be more likely to experience hair loss.

Comparing Hair Loss Risks

Medication

Hair Loss Risk

Patient Group

Additional Notes

Wegovy (Semaglutide)

52% higher

Primarily women

Rapid weight loss potential

Contrave

Baseline risk

Mixed

Less aggressive weight loss

Other GLP-1 Medications

Varies

Individual dependent

Requires further research

What Patients Should Know

If you're considering online weight loss prescriptions, it's essential to discuss potential side effects with a healthcare provider. Hair loss might be temporary and manageable, but individual experiences can vary.

Frequently Asked Questions

No, not all patients experience hair loss. Individual responses differ.

Typically, stress-induced hair loss is temporary and resolves within months.

Protein-rich diets and supplements might mitigate some hair loss risks.

Consult your healthcare provider before making any medication changes.

Your doctor can help explore alternative medications for weight loss.

The Bottom Line

While the potential for hair loss exists, Wegovy remains an effective weight loss solution for many. Each patient's experience is unique, and the benefits may outweigh potential side effects.

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