What Medications Affect Your Cholesterol?
Published: Jun 19, 2024
Did you know that some medications can change your cholesterol levels? Find out which common drugs might be affecting your lipids.
Contents
Impact of Common Medications
Drugs like thiazide diuretics, beta blockers, and oral estrogens can modestly alter lipid levels. These changes might not be significant for everyone, but they can exacerbate existing dyslipidemia, especially in those with other risk factors.
Antipsychotic Medications
Atypical antipsychotics, such as clozapine and olanzapine, are linked to weight gain and lipid changes. They can lead to increased triglycerides and higher risks of diabetes, contributing to an overall metabolic syndrome.

HIV Treatment and Lipids
Some antiretroviral drugs used to treat HIV, particularly protease inhibitors, can disturb lipid and glucose metabolism. This often results in a condition known as lipodystrophy, which can complicate cholesterol management.
Frequently Asked Questions
Yes, several common drugs can alter cholesterol levels.
Yes, they can increase triglycerides and contribute to weight gain.
Some HIV drugs can cause lipid and glucose metabolism issues.
Key Takeaways
Be aware of how your medications might affect your cholesterol and discuss any concerns with your doctor.
References
- Dursun SM, Szemis A, Andrews H, Reveley MA. The effects of clozapine on levels of total cholesterol. J Psychiatry Neurosci 1999; 24:453.
- Osser DN, Najarian DM, Dufresne RL. Olanzapine increases weight and serum triglyceride levels. J Clin Psychiatry 1999; 60:767.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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