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What Are Secondary Causes of Dyslipidemia?
Published: Nov 04, 2023
Dyslipidemia, or abnormal lipid levels in the blood, might not always be due to a primary disorder. Let's explore the secondary causes that often go unnoticed.
Diabetes and Dyslipidemia
In people with type 2 diabetes, insulin resistance often leads to dyslipidemia. This means more triglycerides and low levels of good HDL cholesterol. The severity of insulin resistance can affect the size and number of various lipoprotein particles, worsening the condition.
Liver and Kidney Complications
Certain liver conditions, like primary biliary cholangitis, can cause high cholesterol due to unusual lipoproteins. Kidney issues, such as nephrotic syndrome, also contribute by causing high LDL cholesterol. Even chronic kidney disease can lead to lipid imbalances.
The Impact of Hypothyroidism
Hypothyroidism is a frequent cause of high cholesterol, particularly raising LDL levels. It's important to screen for this condition in anyone with dyslipidemia, as treating the thyroid issue can normalize cholesterol levels.
Frequently Asked Questions
Dyslipidemia is having abnormal levels of lipids, like cholesterol and triglycerides, in the blood.
Diabetes can cause insulin resistance, leading to higher triglycerides and lower HDL cholesterol.
Yes, they can lead to higher LDL cholesterol and other lipid imbalances.
Yes, hypothyroidism often raises LDL cholesterol levels.
Key Takeaways
Understanding the secondary causes of dyslipidemia can lead to more effective treatment strategies.
References
- Vodnala D, Rubenfire M, Brook RD. Secondary causes of dyslipidemia. Am J Cardiol 2012; 110:823.
- Zavaroni I, Dall'Aglio E, Alpi O, et al. Evidence for an independent relationship between plasma insulin and concentration of high density lipoprotein cholesterol and triglyceride. Atherosclerosis 1985; 55:259.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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