GI & Digestive

Why Does My Stomach Hurt More at Night?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 21st, 2026.

Stomach pain often worsens at night due to several physiological factors. When you lie down, stomach acid can more easily flow back into the esophagus, causing heartburn and discomfort. Your body's natural circadian rhythms also reduce digestive activity during nighttime hours, which can slow gastric emptying and increase bloating. Additionally, the stress hormone cortisol naturally decreases in the evening, potentially making you more sensitive to pain signals. Late-night eating compounds these issues by forcing your digestive system to work while in a resting position. Studies show that approximately 75% of people with gastroesophageal reflux disease experience symptoms primarily at night.

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