When Should You Take Nexium Before or After Food?

Nexium should be taken at least one hour before eating for maximum effectiveness. Taking it on an empty stomach allows the medication to be properly absorbed and begin working before acid production increases with food intake. The proton pump inhibitors in Nexium need time to bind to the acid-producing cells in your stomach lining. Clinical studies show that taking Nexium 60 minutes before breakfast provides optimal acid suppression for up to 24 hours. If you miss the morning dose, take it as soon as you remember, but maintain the one-hour gap before your next meal.