Best Time To Take

When Should You Take Medicine That Says Twice a Day?

Andre Stone | MD

Medically reviewed by Andre Stone | MD, University of Pittsburgh School of Medicine on August 25th, 2026.

Many medicines taken twice a day are spaced roughly 12 hours apart, such as in the morning and evening. However, the best schedule depends on the medicine, so follow the prescription label or instructions from your doctor or pharmacist. Some medicines, including certain antibiotics and blood pressure medicines, have specific timing instructions. Follow the label and ask your pharmacist if the schedule is unclear. If you miss a dose, check the medicine label or patient leaflet or ask a pharmacist what to do. Instructions vary by medicine, and you should not take an extra dose unless a healthcare professional or the medicine instructions tell you to. Always follow your pharmacist's specific instructions and ask about timing with meals if unclear.

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