Drug-resistant gonorrhea requires combination antibiotic therapy, typically ceftriaxone plus azithromycin. The CDC recommends dual therapy because single-drug treatments have failure rates exceeding 30% for resistant strains. Ceftriaxone 500mg intramuscularly combined with azithromycin 1g orally remains the standard first-line treatment. For patients with severe allergies or confirmed ceftriaxone resistance, alternative regimens include gentamicin plus azithromycin or cefixime plus azithromycin. Treatment failure occurs in approximately 5-7% of cases with resistant strains. Close follow-up testing 7-14 days after treatment is essential to confirm cure, especially for pharyngeal infections which show higher resistance rates.
What causes gonorrhea to become antibiotic-resistant?
How is drug-resistant gonorrhea diagnosed?
Can drug-resistant gonorrhea be prevented?
Comprehensive overview of current CDC treatment recommendations for gonorrhea infections. Explains when dual therapy is necessary and what to expect during treatment.
Detailed explanation of how sexually transmitted infections develop resistance to antibiotics. Covers prevention strategies and the importance of completing prescribed treatments.
Guide to proper STI testing procedures and post-treatment monitoring. Explains when retesting is necessary and how to prevent reinfection.
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