Birth Control & Women's Health

Does Evening Primrose Oil Help with Period Cramps?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 22nd, 2026.

Evening primrose oil may provide mild relief for period cramps, though scientific evidence remains limited. The oil contains gamma-linolenic acid (GLA), an omega-6 fatty acid that may help reduce inflammation and prostaglandin production. Some studies suggest taking 500-1000mg daily during the second half of your menstrual cycle could help with pain and other PMS symptoms. However, research results are mixed, with some trials showing minimal benefits compared to placebo. Common side effects include nausea and headaches. While generally considered safe, evening primrose oil can interact with blood-thinning medications and may not be suitable during pregnancy.

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