Can You Take Ibuprofen and Acetaminophen Together?

Many adults can take ibuprofen and acetaminophen together for short-term pain relief, but this is not safe for everyone. Check each product’s label and ask a healthcare professional if you are unsure whether either medicine is appropriate for you. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation, while acetaminophen blocks pain signals in the brain. For some types of short-term pain, taking ibuprofen and acetaminophen together may provide better relief than taking either medicine alone. If using both medicines, follow the dose and timing on each product’s label and keep track of the total amount taken in 24 hours. Do not take more than the label allows unless a healthcare professional specifically tells you to. This combination may help with some types of short-term pain, including dental or post-procedure pain. Ask a healthcare professional before using ibuprofen if you have a history of stomach ulcers or bleeding, heart or kidney disease, take blood thinners, are pregnant, or have been told to avoid NSAIDs. Ask before using acetaminophen if you have liver disease, drink alcohol heavily, or take other products containing acetaminophen. Follow your surgeon’s instructions after a procedure.