Sleep

Can Low Iron Cause Insomnia?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 20th, 2026.

Yes, low iron can cause insomnia and other sleep disturbances. Iron deficiency affects the production of neurotransmitters like dopamine and serotonin, which regulate sleep cycles. Studies show that up to 25% of people with restless leg syndrome, a major cause of insomnia, have low iron levels. Iron deficiency can also cause fatigue during the day, leading to irregular sleep patterns at night. Additionally, low iron reduces oxygen transport to tissues, creating physical discomfort that interferes with falling asleep. If you suspect iron deficiency is affecting your sleep, blood tests measuring ferritin levels can confirm the diagnosis and guide appropriate treatment.

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