Yes, low calcium levels can cause muscle cramps and spasms. Calcium plays a crucial role in muscle contraction and nerve function, so when blood calcium drops below 8.5 mg/dL, muscles may contract involuntarily. This condition, called hypocalcemia, affects approximately 2-18% of hospitalized patients. Common symptoms include cramping in the hands, feet, and legs, along with tingling sensations around the mouth. The cramps typically worsen at night and may be accompanied by muscle twitching or tetany. Other causes include vitamin D deficiency, parathyroid disorders, or certain medications like diuretics.
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