Chancroid: A Comprehensive Guide

April 1st, 2026

Key Takeaways

  • Chancroid is a sexually transmitted infection caused by the bacteria Haemophilus ducreyi

  • It causes painful genital ulcers that are soft and tender to touch

  • The infection is more common in developing countries but rare in the United States

  • Early treatment with antibiotics can cure the infection completely

  • Using condoms and limiting sexual partners helps prevent transmission

Overview

Chancroid is a bacterial sexually transmitted infection (STI) that affects the genital area. The bacteria Haemophilus ducreyi causes this condition. It creates painful, open sores called ulcers on or around the genitals.

This infection is much more common in some parts of Africa, Asia, and the Caribbean. In the United States and other developed countries, chancroid is very rare. Most cases here happen in people who traveled to areas where the infection is common.

The infection spreads through sexual contact with someone who has chancroid. Unlike some other STIs, chancroid does not usually cause long-term health problems when treated properly. However, the open sores can increase the risk of getting HIV and other infections.

Chancroid is different from other STIs because the ulcers are very soft and painful. The bacteria that causes it dies when exposed to air, so it only spreads through direct contact. Getting treatment early stops the infection from getting worse and infecting your partners.

Symptoms & Signs

Chancroid symptoms usually appear within 1 to 14 days after exposure. The main sign is one or more painful ulcers on the genitals. These sores look different from other genital ulcers you might know about.

Primary Symptoms

  • Painful genital ulcers - Soft, tender sores that hurt when touched

  • Red bumps - Small raised areas that quickly turn into open sores

  • Swollen lymph nodes - Painful, enlarged glands in the groin area

  • Bleeding ulcers - Sores that may bleed easily when touched

When to Seek Care

See a healthcare provider if you notice any genital sores or ulcers. Get care right away if the sores are very painful or if you have swollen, tender lymph nodes in your groin. Early treatment helps prevent complications and stops the spread to others.

The ulcers from chancroid usually grow larger without treatment. They can become so painful that sitting or walking becomes difficult. If left untreated, the infection can spread to nearby lymph nodes and cause serious swelling.

When to Seek Immediate Care

Contact a healthcare provider immediately if you develop fever, severe pain, or if lymph nodes become very large and tender.

Causes & Risk Factors

Age

Most common in sexually active adults aged 20-40

Travel

Visiting areas where chancroid is endemic increases risk

Multiple Partners

Having several sexual partners raises infection chances

Other STIs

Having HIV or other STIs makes infection more likely

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Diagnosis

Medical History & Physical Examination

Your doctor will ask about your symptoms and sexual history. They need to know about recent sexual partners and any travel to areas where chancroid is common. The doctor will examine the ulcers and check your lymph nodes.

During the exam, your healthcare provider looks at the size, shape, and appearance of any sores. Chancroid ulcers are usually soft and very painful. This helps tell them apart from other types of genital ulcers.

Diagnostic Testing

  • Bacterial culture - Takes a sample from the ulcer to grow the bacteria in a lab

  • PCR testing - Uses genetic material to identify the specific bacteria

  • Blood tests - Checks for other STIs like HIV and syphilis that can look similar

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Treatment Options

The good news is that chancroid responds well to antibiotic treatment. Most people feel better within a few days of starting medication. Treatment also helps prevent spreading the infection to others.

Conservative Treatments

  • Azithromycin - Single dose antibiotic taken by mouth

  • Ceftriaxone - One injection given in the muscle

  • Ciprofloxacin - Antibiotic pills taken for 3 days

Advanced Treatments

  • Erythromycin - Used when other antibiotics cannot be taken due to understanding allergies

  • Drainage procedures - For very large, swollen lymph nodes that need fluid removed

Most doctors recommend finishing all the antibiotics even if you feel better. Stopping early can let the bacteria survive and come back. Your doctor will schedule a follow-up visit to make sure the infection is completely gone.

Living with the Condition

Daily Management Strategies

Keep the affected area clean and dry. Wash gently with soap and water, then pat dry with a clean towel. Avoid tight clothing that might rub against the sores. Take pain medication as needed to stay comfortable.

Avoid sexual activity until your doctor says the infection is completely gone. This usually takes about 7 to 10 days after treatment starts. Your sexual partners also need testing and treatment to prevent reinfection.

It is important to be honest with your healthcare provider about all your symptoms. Tell them about any other health problems you have or medicines you take. This helps them choose the safest treatment for you.

Exercise & Movement

Normal daily activities are fine during treatment. You might feel more comfortable wearing loose-fitting clothes. Swimming in pools or hot tubs should be avoided until the sores heal completely.

Prevention

  • Use latex condoms correctly every time you have sex

  • Limit your number of sexual partners

  • Get tested regularly for STIs if you are sexually active

  • Avoid sexual contact if you or your partner has genital sores

  • Talk openly with sexual partners about STI testing and history

  • Seek prompt treatment if you notice any unusual genital symptoms

Prevention is much easier than dealing with chancroid. Knowing the signs of the infection helps you catch it early. Talking with your partners about sexual health keeps everyone safer.

Frequently Asked Questions

With proper antibiotic treatment, chancroid ulcers usually start healing within 3 to 7 days. Complete healing typically takes 1 to 2 weeks. The pain often gets better within the first few days of treatment.

Chancroid does not come back on its own after successful treatment. However, you can get infected again if you have sexual contact with someone who has the infection. This is why partner treatment is so important.

No, chancroid and herpes are different infections. Chancroid ulcers are usually more painful and softer than herpes sores. Chancroid is caused by bacteria and can be cured with antibiotics, while herpes is viral and stays in your body.

Yes, you should tell recent sexual partners so they can get tested and treated. This helps prevent the infection from spreading and protects everyone involved. Most partners will need treatment even if they don't have symptoms.

Yes, but pregnant women need special antibiotic choices. Some medications used for chancroid are not safe during pregnancy. A healthcare provider can choose the right treatment options that are safe for both mother and baby.

Last Updated: April 1st, 2026
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