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What is Antiphospholipid Syndrome and How Does It Affect You?
Published: Jul 17, 2024
Antiphospholipid syndrome (APS) is a condition that can cause unexpected blood clots and pregnancy complications. Understanding APS is crucial for managing its effects on your health.
Understanding APS
Antiphospholipid syndrome is an autoimmune disorder where the immune system mistakenly attacks normal proteins in the blood. This leads to the formation of antiphospholipid antibodies, which can cause blood clots in veins and arteries. APS can manifest as a primary condition or alongside another autoimmune disease, such as systemic lupus erythematosus (SLE).
Common Symptoms
Symptoms of APS can vary but often include unexplained blood clots or pregnancy issues. Some might experience skin changes like a lacy rash, heart valve problems, or neurological symptoms such as memory loss. Women with APS may face challenges like miscarriages or preterm labor due to complications in pregnancy.
Risk Factors and Diagnosis
Several factors can increase the risk of developing APS, including having another autoimmune disease or a family history of blood clots. Diagnosing APS requires blood tests to detect the presence of antiphospholipid antibodies. These tests need to show positive results on two separate occasions, at least 12 weeks apart, to confirm the diagnosis.
Frequently Asked Questions
APS is caused by the body's immune system mistakenly targeting normal proteins in the blood.
Yes, APS can lead to complications like miscarriages and preterm birth.
APS is diagnosed through blood tests showing antibodies on two separate occasions.
People with other autoimmune diseases or a family history of blood clots are at higher risk.
Key Takeaways
Understanding APS can help manage its complications and improve quality of life.
References
- Garcia D, Erkan D. Diagnosis and Management of the Antiphospholipid Syndrome. N Engl J Med 2018; 378:2010.
- Ruiz-Irastorza G, Crowther M, Branch W, Khamashta MA. Antiphospholipid syndrome. Lancet 2010; 376:1498.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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