Contents
What Increases Your Risk of Antiphospholipid Syndrome?
Published: May 13, 2024
Identifying risk factors for antiphospholipid syndrome (APS) can help prevent its complications. Discover what makes some people more susceptible to this condition.
Genetic and Autoimmune Links
APS risk can be higher in individuals with a family history of autoimmune diseases. It's also commonly seen in people with systemic lupus erythematosus (SLE) or other autoimmune disorders. Genetic predispositions can lead to increased production of antiphospholipid antibodies, setting the stage for APS.
Environmental Triggers
Certain infections or medications can temporarily increase the levels of antiphospholipid antibodies. These transient antibodies might not cause APS but can complicate its diagnosis. Understanding these environmental triggers helps in distinguishing between temporary and persistent antibody presence.
Lifestyle Factors
Lifestyle choices such as smoking or using estrogen-containing contraceptives can amplify the risk of blood clots in individuals with APS. Managing these factors is crucial in preventing thrombotic events and managing APS effectively.
Frequently Asked Questions
A family history of autoimmune diseases can increase APS risk.
Yes, infections can temporarily elevate antibody levels.
Smoking and estrogen use can increase thrombotic risk in APS.
Some medications can temporarily raise antibody levels.
The Bottom Line
Awareness of risk factors can aid in preventing APS complications.
References
- Sebastiani GD, Galeazzi M, Tincani A, et al. Anticardiolipin and anti-beta2GPI antibodies in a large series of European patients with systemic lupus erythematosus. Scand J Rheumatol 1999; 28:344.
- Miyakis S, Lockshin MD, Atsumi T, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006; 4:295.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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