Contents
What Causes Hypercalcemia? Unraveling the Mystery
Published: Sep 30, 2023
Hypercalcemia is a common condition where the calcium levels in the blood are higher than normal. This article explores the causes behind this condition and how they can be identified.
Common Culprits
The most frequent causes of hypercalcemia are primary hyperparathyroidism and malignancy, accounting for over 90% of cases. Hyperparathyroidism is when the parathyroid glands produce too much hormone, while malignancy refers to cancer-related conditions. These two causes often have distinct clinical presentations, helping doctors identify the underlying issue.
Uncommon Causes
While less common, there are other potential causes of hypercalcemia. These include conditions like familial hypocalciuric hypercalcemia, vitamin D intoxication, and certain granulomatous diseases. Each of these conditions has its own unique features and diagnostic criteria, adding complexity to the diagnostic process.
Diet and Medications
Diet and medications can play a role in hypercalcemia. For instance, excessive intake of calcium or vitamin D supplements can lead to elevated calcium levels. Additionally, certain medications, like thiazide diuretics, can cause calcium levels to rise, contributing to the condition.
Frequently Asked Questions
Hypercalcemia is when there's too much calcium in the blood.
The main causes are primary hyperparathyroidism and cancer.
Yes, excessive calcium or vitamin D intake can contribute.
Yes, it can lead to significant health issues if untreated.
The Bottom Line
Identifying the cause of hypercalcemia is crucial for effective treatment.
References
- Lafferty FW. Differential diagnosis of hypercalcemia. J Bone Miner Res 1991; 6 Suppl 2:S51.
- Walker MD, Shane E. Hypercalcemia: A Review. JAMA 2022; 328:1624.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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