What Are the Telltale Symptoms of Antiphospholipid Syndrome?
Published: Jan 23, 2024
Recognizing the symptoms of antiphospholipid syndrome (APS) early can lead to timely intervention and better health outcomes. Let's explore the key signs to watch for.
Contents
Common APS Symptoms
APS can present with a variety of symptoms, primarily due to blood clots forming in veins and arteries. Common signs include unexplained strokes, deep vein thrombosis, and pulmonary embolism. These symptoms often appear in younger individuals and may signal an underlying issue.
Pregnancy-Related Symptoms
In women, APS can lead to complications during pregnancy, such as recurrent miscarriages or preterm births. These complications are often linked to impaired blood flow to the placenta, highlighting the importance of monitoring during pregnancy for women with APS.

Skin and Neurological Symptoms
Some individuals with APS may experience skin changes like livedo reticularis, a lacy, purplish rash. Neurological symptoms can include headaches or cognitive difficulties, which may be related to small blood clots affecting the brain.
Frequently Asked Questions
APS symptoms include strokes, deep vein thrombosis, and pulmonary embolism.
APS can cause miscarriages and preterm births due to placental blood flow issues.
Yes, APS can cause livedo reticularis, a lacy rash on the skin.
Yes, small blood clots in the brain can lead to cognitive issues in APS.
The Bottom Line
Recognizing APS symptoms early is crucial for preventing severe complications.
References
- Cervera R, Asherson RA. Clinical and epidemiological aspects in the antiphospholipid syndrome. Immunobiology 2003; 207:5.
- Love PE, Santoro SA. Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non-SLE disorders. Ann Intern Med 1990; 112:682.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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