Treating Adrenal Insufficiency: Replacing What's Missing
Published: Sep 12, 2023
Treating adrenal insufficiency involves replacing the hormones your body can't produce. While it's not a cure, proper treatment allows most people to lead normal, healthy lives.
Contents
Cortisol Replacement: The Main Treatment
The primary treatment for adrenal insufficiency is replacing cortisol with hydrocortisone pills. Most people take these 2-3 times a day to mimic the body's natural cortisol rhythm. Your doctor will work with you to find the lowest dose that relieves your symptoms. It's crucial to take these medications as prescribed and never skip doses.
Mineralocorticoid Replacement: For Some Patients
If you have primary adrenal insufficiency (Addison's disease), you'll also need to replace aldosterone. This is typically done with a medication called fludrocortisone, taken once daily. This helps regulate your body's salt and water balance. People with central adrenal insufficiency usually don't need this medication.

Adjusting Treatment During Stress
Your body normally produces extra cortisol during times of stress or illness. Since you can't do this naturally, you'll need to increase your medication. This might mean doubling or tripling your usual dose during minor illnesses or injuries. For major stresses like surgery, you may need IV steroids. Your doctor will provide specific instructions for these 'stress doses'.
Frequently Asked Questions
Adrenal insufficiency requires lifelong hormone replacement therapy.
Possible, but minimized by using the lowest effective dose.
Take it as soon as you remember, unless it's almost time for your next dose.
In moderation, but it may affect how your body processes the medication.
Key Takeaways
While managing adrenal insufficiency requires ongoing care, most people achieve excellent quality of life with proper treatment.
Ready to optimize your adrenal insufficiency treatment? Schedule a consultation with Doctronic to review your current regimen and discuss any concerns.Related Articles
References
Bornstein SR, et al. J Clin Endocrinol Metab. 2016;101:364-389.
Husebye ES, et al. Lancet. 2021;397:613-629.
Always discuss health information with your healthcare provider.