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Strep Throat: The Surprising Link to Rheumatic Fever
Published: May 28, 2024
Did you know that a simple sore throat can lead to a serious condition called Acute Rheumatic Fever (ARF)? Here's how it happens.
The Role of Strep Throat
Strep throat, caused by Group A Streptococcus, is more than just a sore throat. If left untreated, it can lead to ARF. The body's immune response to the bacteria can mistakenly target its own tissues, causing inflammation and damage.
How ARF Develops
ARF usually develops 2-3 weeks after a strep infection. During this time, the immune system's antibodies attack the body's own cells, leading to symptoms like joint pain and heart inflammation. This autoimmune response is what makes ARF so dangerous.
Why Some People Are More Susceptible
Certain genetic factors may make some individuals more susceptible to ARF. Research suggests that variations in immune system genes play a role. This genetic predisposition means that not everyone with strep throat will develop ARF, but those who do may have a higher genetic risk.
Frequently Asked Questions
An immune response mistakenly targets the body's tissues.
Usually 2-3 weeks after the infection.
Yes, genetic factors can increase susceptibility.
Wrapping Up
Understanding the link between strep throat and ARF can help in prevention and early treatment.
References
- Rammelkamp CH Jr, Stolzer BL. Yale J Biol Med 1961; 34:386.
- Lawrence JG, Carapetis JR, Griffiths K, et al. Circulation 2013; 128:492.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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