Identifying Symptoms of MGUS: What to Watch For
Published: Dec 28, 2023
While MGUS is often symptomless, recognizing potential symptoms can lead to early intervention. Let's see what to look out for.
Contents
Common Symptoms
Most people with MGUS don't experience symptoms initially. However, if MGUS progresses, symptoms like bone pain, fatigue, or unexplained weight loss may appear. It's important to stay alert for these signs and consult a doctor if they occur.
When to Seek Help
If you notice persistent symptoms such as bone pain or fatigue, it might be time to seek medical advice. Early detection can lead to better management of any potential progression to more serious conditions.

Monitoring for Change
Regular check-ups and blood tests are crucial for those diagnosed with MGUS. These help in catching any changes early, even before symptoms become noticeable.
Frequently Asked Questions
No, MGUS is often symptomless.
Watch for bone pain, fatigue, or weight loss.
Consult a doctor if symptoms persist or worsen.
Wrapping Up
Being aware of MGUS symptoms can aid in early intervention and management.
References
- Kyle RA, Durie BG, Rajkumar SV, et al. Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management. Leukemia 2010; 24:1121.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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