How Can We Prevent the Progression of MGUS?
Published: Apr 21, 2024
MGUS can progress to serious diseases, but there are ways to monitor and manage this risk. Let's dive into prevention strategies.
Contents
Monitoring MGUS Progression
Regular monitoring is key to managing MGUS. Patients should have their blood tested every six months initially, and then yearly if stable, to check for changes that might indicate progression to a more serious condition.
Risk Stratification
Doctors use a system to estimate the risk of progression based on factors like M-protein levels and light chain ratios. This helps determine how often patients should be tested and monitored to catch any early signs of disease progression.

The Role of Lifestyle
Maintaining a healthy lifestyle with a balanced diet and regular exercise can support overall health. While lifestyle changes alone may not prevent MGUS progression, they can contribute to better health outcomes.
Frequently Asked Questions
MGUS should be monitored every six months initially, then yearly if stable.
M-protein levels and light chain ratios are key factors.
While not directly preventive, a healthy lifestyle supports overall well-being.
Wrapping Up
Monitoring and risk assessment are vital in preventing MGUS progression.
References
- Kyle RA, Therneau TM, Rajkumar SV, et al. A long-term study of prognosis in monoclonal gammopathy of undetermined significance. N Engl J Med 2002; 346:564.
- Kyle RA, Larson DR, Therneau TM, et al. Long-Term Follow-up of Monoclonal Gammopathy of Undetermined Significance. N Engl J Med 2018; 378:241.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
AI Doctor Visit Required
Appointments available 24/7
15-min consultation. No hidden costs.
AI Doctor Visit Required
For safety reasons we have been forced to end this consultation.
If you believe this is a medical emergency please call 911 or your local emergency services immediately.
If you are experiencing emotional distress, please call the the Suicide & Crisis Lifeline at 988 or your local crisis services immediately.
Contact us
You can also email us at help@doctronic.ai
We aim to reply within 5-7 days
How likely are you to recommend Doctronic to friends or family?