How is Hypocalcemia Diagnosed?
Published: Nov 14, 2023
Accurate diagnosis of hypocalcemia is essential for effective treatment. Discover the tests and techniques used to identify this condition.
Contents
Understanding Serum Calcium Levels
Calcium in the blood is mostly attached to a protein called albumin. This means that your total calcium level might not accurately reflect your 'free' calcium, which is the active form your body uses. Doctors often correct calcium levels based on albumin levels to get a clearer picture of your calcium status.
The Role of Ionized Calcium Tests
Ionized calcium tests measure the free calcium in your blood, giving a more accurate assessment of your calcium status. This test is particularly useful if you're experiencing unusual symptoms or have abnormal albumin levels. Although more expensive, it's often considered the gold standard for diagnosing hypocalcemia.

When to Use Correction Formulas
If ionized calcium testing isn't available, doctors may use formulas to estimate your calcium level based on albumin. These formulas help adjust the total calcium level to reflect what it would be if albumin were normal. However, their accuracy can vary, so results should be interpreted with caution.
Frequently Asked Questions
It measures the amount of calcium in your blood.
It measures the active form of calcium, providing a more accurate diagnosis.
Albumin levels can affect total calcium test results.
Key Takeaways
Understanding your calcium test results is crucial for diagnosing and managing hypocalcemia effectively.
References
- Cooper MS, Gittoes NJ. Diagnosis and management of hypocalcaemia. BMJ 2008; 336:1298.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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