How Effective Are Current Therapies for Dementia with Lewy Bodies?
Published: Oct 30, 2023
While no cure exists for DLB, various treatments aim to manage symptoms and improve patient quality of life. Here's a look at the options.
Contents
Pharmacologic Treatments
Cholinesterase inhibitors and memantine are the primary drugs used in DLB treatment. They aim to improve cognitive and behavioral symptoms. However, their effectiveness varies, and they may have side effects like nausea and confusion.
Managing Parkinsonian Symptoms
Levodopa is often used to treat parkinsonian symptoms in DLB. It can improve mobility but may worsen psychiatric symptoms. A conservative approach with low doses is recommended to minimize adverse effects.
Non-Drug Approaches
Non-drug therapies include lifestyle changes and environmental modifications. These strategies can reduce stress and improve symptom management, enhancing the quality of life for both patients and caregivers.
Frequently Asked Questions
Cholinesterase inhibitors and memantine.
It improves mobility but may worsen psychiatric symptoms.
Yes, they help manage symptoms and reduce stress.
Nausea and confusion are common side effects.
Key Takeaways
A combination of pharmacologic and non-drug approaches is key to managing DLB.
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References
McKeith I, Del Ser T, Spano P, et al. Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study. Lancet 2000; 356:2031.
Molloy S, McKeith IG, O'Brien JT, Burn DJ. The role of levodopa in the management of dementia with Lewy bodies. J Neurol Neurosurg Psychiatry 2005; 76:1200.
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