Guidelines for Managing Hypercalcemia in Cancer
Published: Dec 22, 2023
Following guidelines can make managing hypercalcemia in cancer patients more effective and efficient.
Contents
Initial Assessment
Start by measuring serum calcium levels to confirm hypercalcemia. Next, check PTH levels to differentiate between primary hyperparathyroidism and other causes. This sets the stage for further testing and management.
Further Diagnostic Tests
If PTH is low, measure PTHrP and vitamin D metabolites. These tests help identify humoral hypercalcemia of malignancy and vitamin D intoxication. Proper diagnosis is crucial for effective treatment.

Treatment Approach
Immediate treatment typically involves hydration and medications like bisphosphonates. These treatments help lower calcium levels and manage symptoms. Long-term treatment plans may vary based on the underlying cause.
Frequently Asked Questions
Measure serum calcium levels.
It suggests causes other than primary hyperparathyroidism.
They help lower calcium levels effectively.
Wrapping Up
Adhering to guidelines can lead to better outcomes for cancer patients with hypercalcemia.
References
- Horwitz MJ. Non-parathyroid hypercalcemia. Primer on Metabolic Bone Diseases, 2018.
- Wimalawansa SJ. Significance of plasma PTH-rp in hypercalcemia. Cancer 1994; 73:2223.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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